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Ultra Low-Power Biomedical Signal Processing

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  • Saadedin
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    • Sep 2018 
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    Ultra Low-Power Biomedical Signal Processing







    Introduction

    Around 40% of all human deaths are attributed to cardiovascular diseases.

    A practical way to decrease the overall cardiac mortality and morbidity is to

    supply patients at risk with an implantable device, known as artificial pacemaker,

    that is designed to monitor the cardiac status and to regulate the

    beating of the heart. Cardiac pacing has become a therapeutic tool used

    worldwide with over 250,000 pacemaker implants every year.



    Cardiac pacemakers include real-time sensing capacities reflecting the state

    of the heart. Current pacemaker detection circuitry can be interpreted as a

    cardiac electrical signal compression algorithm squeezing the time signal information

    into a single event representing the cardiac activity. Future cardiac

    pacing algorithms, however, are believed to take advantage of the morphological

    aspects of the sensed cardiac signal, improving the analysis and the

    recording of relevant cardiac activity data via implantable sensors. This will

    provide, for instance, a new opportunity for monitoring and managing infarctthreatened

    patients and post-infarction patients outside the hospital.

    In implantable medical devices, such as pacemakers, power consumption

    is critical, due to the limited power density and the longevity of currently

    available portable batteries. This implies that the design of such devices has

    to be optimized for very low power dissipation.

    The purpose of this book is to detail the significant advances in cardiac

    pacing systems and to develop novel signal processing methodologies and analog

    integrated circuit techniques for low-power biomedical systems.





    Biomedical signal processing

    Biomedical signal processing centers on the acquisition of vital signals extracted

    from biologic and physiologic systems. These signals permit us to

    obtain information about the state of living systems, and therefore, their monitoring

    and interpretation have significant diagnostic value for clinicians and

    researchers to obtain information related to human health and diseases.

    The processing of biomedical signals strongly depends on the knowledge

    about the origin and the nature of the signal and poses many special properties,

    which usually presents some unique problems. The reason for this is mainly

    due to the complexity of the underlying biologic structures and their signals,

    and the need to perform indirect, non-invasive measurements. In addition, the

    detected signals are commonly corrupted with noise, and thus, the relevant

    information is not “visible” and cannot be readily extracted from the raw

    signal. For such reasons, advanced signal processing is usually required.

    Another important aspect of biomedical signals is that the information of

    interest is often a combination of features that are well localized temporally

    (e.g., spikes) and others that are more diffuse (e.g., small oscillations) [1]. This

    requires the use of analysis methods sufficiently versatile to handle events that

    can be at opposite extremes in terms of their time–frequency localization. In

    this book, we will investigate the ability of the wavelet analysis to extract

    information from a biomedical signal.







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